I've used many tools, and I've come to the conclusion that the most important things are:

Keep one list. And work from it diligently.

Higher-levels of capacity

Inevitably, the limits of a single list get pushed. Too many things to track tempt the creation of a second list, or additional app to track the excess, overflowing data. Don't. Create a longer list and at the bottom, feel okay with throwing stuff below the "Icebox" or "Somebody Maybe" markers.

Make all artifacts meaningful

Meaningful means:

• Identified as a task - ie: reading
• Identified as a reference

When creating a Reference. Think about what contexts you may want to retrieve it in. It is not necessary to be exhaustive, but give it a few seconds of good, honest thought, and tag it accordingly, to make its retrieval easier and more contextual in the future.